Abstract: IoT technologies have the ability to reshape the management and operation of working environments. Specifically for Universities, given their extended societal and technological footprint, such facilities may act as significant catalysts in this process. The presentation will focus on the experiences from the design, installation and initial operation of a Smart and Sustainable Campus environment at Harokopio University of Athens. The facility has a three-fold approach, aiming to enhance the educational, research-oriented and operational needs of day to day activities. Issues with relation to the technical design, technology and sensor selection, daily sustainable operation as well as indicative analytics use cases are presented, that demonstrate the system's benefits and its potential influence on a university's activities.